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GENETIC MANIPULATION WITH MRNA VIA CRISPR CAS9

Speech by Jennifer Doudna in 2016 at the World Economic Forum.


Considered the biggest breakthrough in genetic science this century, CRISPR is the acronym for a molecular toolkit that allows scientists to precisely modify the genetic code of living organisms. Strictly speaking, the acronym stands for "clustered regularly inter-spaced short palindromic repeats", a pattern in the DNA of bacteria first noticed in 1987. For years, the role of this pattern was mysterious, but in the mid-2000s evidence surfaced suggesting that it was part of bacteria's anti-virus defense system. Studies showed that bacteria took parts of a virus' DNA and built it into their own genome using an enzyme code-named Cas-9. The resulting CRISPR sequences allowed the bacteria to detect an attack and fight back.

But the most important breakthrough came in 2012, when teams in the US and Europe led by Jennifer Doudna and Emmanuelle Charpentier showed how the immune system could be turned into a "cut and paste" tool for editing gene sequences with mRNA.

However, another US team was ahead of them with a patent for using the method on human cells, leading to a legal battle over priority - and in February 2017, the US patent office ruled against Doudna and Charpentier. Despite this, they are widely regarded by fellow scientists as the real pioneers of CRISPR.


The technology has evolved so much since 2016 that everything can be genetically designed and engineered : animals, plants and humans. Even babies can be placed on order " by design ".

The danger of mRNA and Crispr Cas9 is that, if used for the wrong purposes, the genetic material of entire peoples can be altered by a single injection. All it takes for this to happen is a plandemic and a well-orchestrated fear psychosis that makes everyone voluntarily run to a vaccination center.




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